White list
Melodyne plugin operates flawlessly with these hosts:
Ableton Live 5.2, 6.x & 7.0.x
Apple GarageBand '08
Apple Logic Pro 7.1, 7.2.x & 8
Apple Soundtrack Pro 2
Cakewalk Sonar 6, 7 & 8
Digidesign Pro Tools HD 7.2, 7.3, 7.4cs3 & 7.4.1
(with 7.2 you have to set the Playback Engine to 1 RTAS Processor. With 7.3 or later Melodyne plugin works with any count of RTAS processors)
Digidesign Pro Tools LE/MP 7.1, 7.3 & 7.4cs3
(with 7.1 you have to set the Playback Engine to 1 RTAS Processor. With 7.3 or later Melodyne plugin works with any count of RTAS processors)
Magix Samplitude 9 & 10
Merging Technologies Pyramix 6 SP1 (to be released soon), for Masscore and Native platforms (the Mykerinos platform can't run Melodyne plug-in)
MotU Digital Performer 5 & 6.01 (Core Audio only, no DAE)
Steinberg Cubase 4.1.x, 4.5.2
Steinberg Nuendo 4.1.x, 4.5.2
Black list
Melodyne plugin doesn't work with these hosts:
Adobe Audition
Digidesign Pro Tools 6.9 and earlier
MotU Digital Performer when used in DAE mode (DP, however, works well with Core Audio)
Soundscape